NAD+ (Nicotinamide Adenine Dinucleotide) is an endogenous nucleotide derived coenzyme studied extensively in laboratory research for its role in cellular metabolism, energy transfer, and genomic maintenance pathways. It is present in all living cells and is investigated for its involvement in a wide range of redox dependent biochemical processes.
In experimental research models, NAD⁺ functions as a central electron carrier, cycling between its oxidized form (NAD⁺) and reduced form (NADH). This redox pairing is examined for its role in mitochondrial energy metabolism, glycolytic pathways, and broader cellular bioenergetics. Beyond redox chemistry, NAD⁺ is also studied as a signaling molecule, including research into its involvement in calcium dependent signaling mechanisms and cellular stress response pathways.
Scientific literature describes multiple biosynthetic routes for NAD⁺ production, including the de novo pathwayoriginating from tryptophan and several salvage pathways utilizing precursors such as nicotinamide, nicotinic acid, nicotinamide riboside, and nicotinamide mononucleotide. These pathways are evaluated in laboratory settings for their contribution to intracellular NAD⁺ availability and metabolic regulation.
Once synthesized, NAD⁺ is associated with participation in hundreds of enzymatic reactions, serving as a cofactor for enzymes involved in metabolic flux, DNA associated processes, and cellular homeostasis. These properties make NAD⁺ a compound of interest in experimental studies focused on energy metabolism, cell signaling, and molecular regulation.
NAD+ is supplied strictly for laboratory and in vitro research use only. This compound is not intended for human or animal consumption, clinical application, diagnostic use, or therapeutic purposes.
NAD+ is supplied strictly for research use only and is not intended for human or animal consumption, clinical application, diagnostic use, or therapeutic purposes.
